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GWAS-related eQTLs across different cancer types

We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).



e.g., "STAD"
e.g., "r²>= 0.8"
e.g., "rs2273"
Cancer type
eQTL type
tagSNP
LD
SNP ID
SNP position (hg19)
Gene symbol
Gene position (hg19)
Beta
t-stat
p-value
GWAS-Traits
THCA cis rs853679 1 rs9986596 chr6:28219661 ZNF193 chr6:28193067-28201260:+ 0.2 3.62 0.000323 Depression
THCA cis rs853679 1 rs9986596 chr6:28219661 ZNF323 chr6:28292517-28324048:- 0.43 5.79 1.25E-8 Depression
THCA cis rs853679 1 rs9986596 chr6:28219661 ZNF389 chr6:28129551-28137375:+ -0.49 -6.86 2.12E-11 Depression
THCA cis rs853679 1 rs9986596 chr6:28219661 ZSCAN23 chr6:28393287-28411279:- 0.23 4.95 1.05E-6 Depression
THCA cis rs875971 1 rs9986696 chr7:65704576 ASL chr7:65540776-65558321:+ 0.16 4.19 3.29E-5 Aortic root size
THCA cis rs875971 1 rs9986696 chr7:65704576 GUSB chr7:65425675-65447246:- -0.27 -5.35 1.35E-7 Aortic root size
THCA cis rs875971 1 rs9986696 chr7:65704576 RABGEF1 chr7:66093890-66276446:+ -0.65 -13.96 2.22E-37 Aortic root size
THCA cis rs9987289 1 rs9987289 chr8:9183358 SGK223 chr8:8175259-8239257:- 0.32 3.35 0.00086 C-reactive protein levels or triglyceride levels (pleiotropy);HDL cholesterol;HDL Cholesterol - Triglycerides (HDLC-TG);C-reactive protein levels or LDL-cholesterol levels (pleiotropy);Cholesterol, total;C-reactive protein levels;C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Metab
THCA cis rs9987353 1 rs9987353 chr8:9116349 SGK223 chr8:8175259-8239257:- 0.39 6.76 4.02E-11 Recombination measurement
THCA cis rs6988636 1 rs9987357 chr8:124187620 FAM83A chr8:124191287-124222317:+ -0.34 -4.39 1.41E-5 Urinary uromodulin levels
THCA cis rs9988450 1 rs9988450 chr1:62924448 DOCK7 chr1:62920398-63153969:- -0.1 -4.02 6.64E-5 Triglycerides
THCA cis rs9783347 1 rs9988866 chr11:18392983 GTF2H1 chr11:18343816-18388590:+ 0.35 9.46 1.42E-19 Pancreatic cancer
THCA cis rs10935120 1 rs9989967 chr3:134238964 ANAPC13 chr3:134196547-134204865:- 0.37 11.72 4.84E-28 Height
THCA cis rs10935120 1 rs9989967 chr3:134238964 CEP63 chr3:134204575-134293852:+ 0.3 6.49 2.09E-10 Height
THCA cis rs9990333 1 rs9990333 chr3:195827205 SDHAP2 chr3:195384910-195415733:+ -0.21 -4.14 4.16E-5 Iron status biomarkers (transferrin saturation);Iron status biomarkers (transferrin levels)